Beyond the common side effects, medication for anxiety comes with
additional risks. While the tranquilizing anti-anxiety drugs are relatively
safe when taken only occasionally and in small doses, they can lead to severe
problems when combined with other substances or taken over long periods of
time.
Furthermore, some people will have adverse reactions to any amount of
anti-anxiety medication. They are not safe for everyone, even when used
responsibly.
Drug interactions and overdose
Used alone, anti-anxiety medications such as Xanax or Valium
rarely cause fatal overdose, even when taken in large doses. But when combined
with other central nervous system depressants, the toxic effects of these
anxiety medications increase.
Taking anti-anxiety medication with alcohol, prescription
painkillers, or sleeping pills can be deadly. Dangerous drug interactions can also occur when
anti-anxiety drugs are taken with antihistamines, which are found in many
over-the-counter cold and allergy medicines. Antidepressants such as Prozac and
Zoloft can also heighten their toxicity. Always talk to your doctor or
pharmacist before combining medications.
Anti-anxiety drug risk
factors
Anyone who takes anti-anxiety medication can experience unpleasant
or dangerous side effects. But certain individuals are at a higher risk:
§ People over 65. Older adults are more sensitive to the
sedating effects of anti-anxiety medication. Even small doses can cause
confusion, amnesia, loss of balance, and cognitive impairment that looks like
dementia. Anti-anxiety drug use in the elderly is associated with an increased
risk of falls, broken hips and legs, and car accidents.
§ Pregnant women. Expectant mothers should avoid
anti-anxiety drugs. Since these anxiety medications cross the placenta, their
use during pregnancy can lead to dependence in the baby. Following birth, the
baby will then go through withdrawal, with symptoms such as muscle weakness,
irritability, sleep and breathing problems, and trembling. These anxiety drugs
are excreted in breast milk, so they should be avoided while breastfeeding, too.
§ People with a history of substance abuse. Anyone with a current or former problem
with alcohol or drugs should avoid anti-anxiety drugs or use them only with
extreme caution. The greatest benefit of benzodiazepines is that they work
quickly, but this also makes them addictive. This can quickly lead to their
abuse, often in dangerous combination with alcohol or other illicit drugs.
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